Cardiology

Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Neena Abraham, MD, MS Knowing how to manage anticoagulants and antithrombotics during acute GI bleeding is essential in preventing avoidable complications, including thromboembolism and delayed hemostasis. Dr. Peter Buch sits down with Dr. Neena Abraham to discuss the latest recommendations from major GI and cardiology societies and explore practical strategies for anticoagulant reversal, triage criteria, and endoscopic hemostasis. Dr. Abraham is a Professor of Medicine and the Medical Director of the Cardiogastroenterology Clinic at the Mayo Clinic in Phoenix.

Faculty: Kevin Alexander, MD This brief clinical discussion examines findings presented at the ESC Heart Failure 2025 meeting in Belgrade, Serbia, on the impact of acoramidis in transthyretin amyloid cardiomyopathy (ATTR-CM). The analysis highlights a reduction in atrial fibrillation events and an improvement in cardiovascular outcomes among patients treated with acoramidis, including those with both wild-type and variant transthyretin (TTR). Data from the ATTRibute-CM study are reviewed, showing associations between treatment and increased serum TTR levels, delayed time to first cardiovascular hospitalization, reduced NT-proBNP levels, and lower all-cause mortality. These results suggest a clinically meaningful benefit of acoramidis and support its potential role in managing ATTR-CM.

Faculty: Ahmad Masri, MD, MS Review findings from the UK Biobank presented recently at the Peripheral Nerve Society meeting, revealing that naturally low transthyretin (TTR) levels are associated with a higher prevalence of cardiovascular biomarkers, such as NT-proBNP, and comorbidities, including peripheral arterial disease, stroke, and cognitive decline. The data suggest that low TTR may serve as a marker of broader systemic illness, both in patients with TTR amyloidosis and in the general population.

Guest: Parul Rai Cardiopulmonary complications are a leading cause of early mortality in adults with sickle cell disease, with evidence showing that cardiac injury may begin as early as childhood. However, despite the severity of these issues, there are currently no uniform guidelines for asymptomatic cardiac screening in this population. Join Dr. Parul Rai, a physician in the Department of Hematology at St. Jude’s Hospital in Memphis, Tennessee, to learn about current research, early detection strategies, and the need for more sensitive diagnostic markers to prevent severe cardiac outcomes in patients with sickle cell disease.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Jeff Brandes By embedding evidence-based metrics directly into existing workflows, the partnership between the American Medical Association (AMA) and Azara Healthcare supports providers in proactively managing hypertension. To learn more about how integrating the AMA MAP™ Hypertension Quality Improvement Program into Azara’s population health tools empowers clinicians to seamlessly deliver guideline-driven care, Dr. Charles Turck speaks with Mr. Jeff Brandes, President and CEO of Azara Healthcare.

Guest: Andrew Goldstone, M.D., Ph.D. On this episode of Advances in Care, host Erin Welsh talks to Dr. Andrew Goldstone, pediatric cardiac surgeon at NewYork-Presbyterian and Columbia, about the groundbreaking heart transplant that saved the lives of three separate children. It was the first time doctors at NewYork-Presbyterian Morgan Stanley Children’s Hospital performed a split-root domino partial heart transplant. In this procedure, one child was transplanted with a new heart and their original heart was used to donate living pulmonary and aortic valves to two separate recipients in need. Dr. Goldstone, his colleague Dr. David Kalfa, and the rest of the team at NewYork-Presbyterian and Columbia had previous experience with a handful of domino partial heart transplants where one patient is transplanted with a new heart and another receives a valve from the explanted heart. Those experiences helped prepare for the split-root domino, which took nearly 24 hours of extremely coordinated care. In addition to their efforts to increase the number of domino heart transplants being done, physician-researchers at the institution are leading new studies that are also helping improve living valve procurement and storage, allowing more children to receive heart valves that will grow with them and require less surgeries. © 2025 …

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Faiyaz Syed MD, MPH The Michigan Primary Care Association (MPCA) recently partnered with the AMA to implement the AMA MAP™ Hypertension Quality Improvement Program at two pilot health centers. After this collaboration resulted in a 6 percent improvement in hypertension control, it’s now expanding to all other MPCA health centers and could even focus on other conditions like diabetes. Joining Dr. Mary Katherine Cheeley to share his experience with the AMA MAP™ program is Dr. Faiyaz Syed, Chief Medical Officer for the MPCA.

Guest: Muthiah Vaduganathan, MD, MPH Guest: Anuradha Lala-Trindade, MD Guest: Brendon Neuen, MBBS, PhD Heart failure with mildly reduced ejection fraction (HFmrEF) and preserved ejection fraction (HFpEF) represent a significant and growing burden for patients and the healthcare system, not only in cardiovascular medicine, but also in the context of cardio-kidney-metabolic (CKM) syndrome. Trials are underway evaluating new therapies that may offer benefits to patients with HFmrEF/HFpEF and may also have broader, multisystem effects. Tune in to stay up to date!

Host: Alejandro A. Rabinstein, MD, FAHA Guest: Richard E. Pratley, MD Guest: Jay H. Shubrook, DO, FACOFP, FAAFP Listen to expert faculty discuss the role of GLP-1RAs in reducing stroke risk for patients with type 2 diabetes in this on-demand webcast with accompanying slides

Host: Riccardo Maria Inciardi, MD, PhD Listen to Dr. Riccardo Inciardi’s summary from the ESC Preventive Cardiology 2025 meeting, where he highlights new therapies reshaping the management of cardio-kidney-metabolic (CKM) syndrome and heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF). Watch as he breaks down the latest clinical trial data showing that SGLT2 inhibitors, GLP-1 receptor agonists, and the nonsteroidal MRA finerenone can meaningfully reduce hospitalizations, kidney disease progression, and cardiovascular mortality. A real-life patient case illustrates how combining these therapies—under the care of a multidisciplinary team—can transform outcomes.

Host: Rishi Wadhera, MD, MPP, Mphil Guest: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Rishi Wadhera, MD, MPP, Mphil Guest: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.

Host: Ty J. Gluckman, MD, MHA, FACC, FAHA, FASPC Guest: Rishi Wadhera, MD, MPP, Mphil Join our experts for case-based episodes that focus on bridging the gap between rural health and cardiovascular disease. Experts will explore ASCVD prevention and treatment by reviewing patient risk factors and determining ASCVD risk reduction strategies. This activity is designed to empower healthcare professionals with the knowledge and tools needed to make impactful decisions in cardiovascular care.