Neurology and Neurosurgery

Guest: Marisa McGinley, DO The multiple sclerosis (MS) treatment landscape is rapidly evolving, with novel approaches on the horizon that may transform care for progressive patients. Explore the latest phase 3 data on BTK inhibitors like tolebrutinib and gain insights into ongoing CAR T-cell and remyelination research, including the BEAT-MS trial, with Dr. Marisa McGinley, a neurologist at the Cleveland Clinic.

Since 2010, the landscape of multiple sclerosis care has transformed to encompass a variety of medications, each having unique benefits, risks, and side effect profiles. Dr. Jonathan Howard discusses how to match treatment strength to disease severity and balance patient risk tolerance with evolving therapeutic options, from long-standing injectables to infusions and oral therapies. Dr. Howard is an Associate Professor of Neurology and Psychiatry at the NYU Grossman School of Medicine and the Director of the Neurology Service at Bellevue Hospital in New York.

Early symptoms of multiple sclerosis (MS) often present as clear, localized neurological changes lasting several days. However, many nonspecific complaints and common MRI findings can mimic MS, leading to misdiagnosis and unnecessary treatment. Dr. Jonathan Howard, an Associate Professor of Neurology and Psychiatry at the NYU Grossman School of Medicine and the Director of the Neurology Service at Bellevue Hospital, reviews hallmark symptom patterns, explains how to differentiate benign MRI changes from true disease, and underscores the importance of thorough history-taking, neurological exams, and targeted testing to ensure accurate diagnosis and optimal patient care.

Guest: David Gate, PhD Patients with Alzheimer's disease—especially APOE4 carriers—show distinct epigenetic immune alterations that may influence disease progression, treatment response, and side effect risk. In this episode, Dr. David Gate, an Assistant Professor of Behavioral Neurology at Northwestern University, dives into his research on this subject and explains how chromatin accessibility in proinflammatory genes and T-cell receptor changes link to neurological pathology.

Guest: Marisa McGinley, DO The MS treatment landscape is rapidly evolving, with novel approaches on the horizon that may transform care for progressive patients. Explore the latest phase 3 data on BTK inhibitors like tolebrutinib and gain insights into ongoing CAR T-cell and remyelination research, including the BEAT-MS trial, with Dr. Marisa McGinley, a neurologist at the Cleveland Clinic.

Guest: Marisa McGinley, DO Multiple sclerosis (MS) presents a diverse range of symptoms, requiring coordinated expert care. Hear from Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, as she provides practical strategies for neurologists to serve as the central point of contact for patients with MS and engage with specialty teams to provide personalized care.

Guest: Marisa McGinley, DO Multiple sclerosis (MS) presents a diverse range of symptoms that require coordinated, expert care. Dr. Marisa McGinley, a neurologist at the Cleveland Clinic, provides practical strategies for neurologists to serve as the central point of contact for patients with MS, initiate targeted treatments, and engage a variety of specialty teams in collaborative management.

Host: Ryan Quigley Guest: Lyn R. Griffiths Decades of research have transformed our understanding of migraine genetics, from rare monogenic types to complex polygenic forms. Mr. Ryan Quigley is joined by Dr. Lyn Griffiths to explore polygenic risk scores, emerging diagnostic tools, and the promise of personalized medicine in migraine care. Dr. Griffiths is a Distinguished Professor and the Director of the Centre for Genomics and Personalised Health at Queensland University of Technology in Brisbane, Australia.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Rashmi B. Halker Singh, M.D. Stigma and misconceptions around migraine can lead to misdiagnosis, undertreatment, and inequitable care, especially in emergency and primary care settings. Listening to patients, validating lived experiences, and enhancing clinical training to recognize migraine as a complex neurologic disorder can help shift the narrative. Learn more as Dr. Charles Turck speaks with Dr. Rashmi Halker Singh about how we can prioritize inclusive, informed, and effective migraine management. Dr. Halker Singh is a Professor of Neurology, and she sits on the Executive Board of Directors at the American Headache Society.

Host: Crystal Proud, MD Guest: Erika Finanger, MD, MS By completing this activity, learners will gain the skills and confidence to determine therapeutic candidacy and conduct appropriate assessments for patients with Duchenne Muscular Dystrophy (DMD) across the age spectrum, including older and non-ambulatory individuals. They will improve their ability to interpret and apply the latest clinical data to real-world scenarios and make informed decisions about treatment and monitoring. Through case-based education, learners will enhance their competence in aligning patients to appropriate therapies and managing long-term care in a rapidly evolving treatment landscape.

A secondary analysis of eight clinical trials assessed the efficacy of ubrogepant and atogepant in both acute and preventive migraine treatments. Dive into these findings and explore implications for the future of migraine care.

Guest: Raman Sankar, MD, PhD Guest: Scott Aaronson, MD This series of bite-sized episodes contains important information on using vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) and treatment-resistant depression (TRD). Drs. Raman Sankar and Scott Aaronson discuss best practices for identifying and treating patients as well as programming strategies for VNS.

Guest: Raman Sankar, MD, PhD Guest: Scott Aaronson, MD This series of bite-sized episodes contains important information on using vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) and treatment-resistant depression (TRD). Drs. Raman Sankar and Scott Aaronson discuss best practices for identifying and treating patients as well as programming strategies for VNS.

Guest: Raman Sankar, MD, PhD Guest: Scott Aaronson, MD This series of bite-sized episodes contains important information on using vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) and treatment-resistant depression (TRD). Drs. Raman Sankar and Scott Aaronson discuss best practices for identifying and treating patients as well as programming strategies for VNS.

Guest: Raman Sankar, MD, PhD Guest: Scott Aaronson, MD This series of bite-sized episodes contains important information on using vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) and treatment-resistant depression (TRD). Drs. Raman Sankar and Scott Aaronson discuss best practices for identifying and treating patients as well as programming strategies for VNS.

Guest: Raman Sankar, MD, PhD Guest: Scott Aaronson, MD This series of bite-sized episodes contains important information on using vagus nerve stimulation (VNS) for the treatment of drug-resistant epilepsy (DRE) and treatment-resistant depression (TRD). Drs. Raman Sankar and Scott Aaronson discuss best practices for identifying and treating patients as well as programming strategies for VNS.

Guest: Andrew G. Lee, MD Host: Ashley Baker, MSN, PMHNP Tailored, team-based care is essential for optimal outcomes in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Ashley Baker sits down with Dr. Andrew Lee to learn more about the diagnostic complexities of the disease, the critical role of neuro-opthalmology, and the importance of shared decision making in creating individualized care plans.

Guest: John Golden Guest: Michael Greenberg, MD EEG-guided headphones from Vital Neuro present a new frontier in anxiety management through personalized, real-time neurofeedback and music therapy. Dr. Michael Greenberg speaks with Vital Neuro CEO John Golden about the science behind these devices, their effectiveness in reducing anxiety symptoms, and how they can integrate into daily life.

Guest: John Golden Host: Michael Greenberg, MD Neuro-responsive EEG headphones are helping healthcare professionals combat burnout by promoting calm, focus, and resilience. Backed by neuroscience and real-time brain monitoring, this personalized technology blends music and neurofeedback to optimize mental states and reduce stress. Hear from Vital Neuro CEO John Golden as he joins Dr. Michael Greenberg to discuss this device's impact in clinical workflows, from pre-op anxiety management to enhanced physician well-being.

Guest: Nicolas Dubuisson, MD Host: Ryan Quigley Early recognition of CIDP is essential to prevent irreversible damage and guide appropriate treatment, but its varied presentations can complicate diagnosis. Ryan Quigley sits down with Dr. Nicolas Dubuisson to discuss the clinical hallmarks of CIDP, its variants, and key risk factors. Dr. Dubuisson is a Postdoctoral Researcher at the Nuffield Department of Clinical Neurosciences at Oxford University in England.